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Old 04-10-2003, 02:49 PM   #1
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Default Primate cloning fails

Primate Cloning Fails
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Navara says the cloned cells simply didn't develop properly in fundamental ways. He says something "critical" is pulled out during the initial stage where the DNA is stripped from the original cell.

That "something," the researchers believe, is motor proteins. Motor proteins, says Navara, organize DNA properly before a cell divides and grows. If the DNA doesn't duplicate itself perfectly before the cell divides, normal growth can't occur, he says.

In other animals, Navara says that motor proteins are more evenly distributed throughout the cell. In primates, however, they appear to be clustered in specific areas that are stripped in the first stage of the process.
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Old 04-10-2003, 03:15 PM   #2
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But... But... But... The Raelians!

They couldn't be wrong, could they?
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Old 04-10-2003, 03:55 PM   #3
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Originally posted by Grumpy
But... But... But... The Raelians!

They couldn't be wrong, could they?
Of course not. They've obviously found a way to strip DNA from a primate cell in a way that doesn't toss the motor protein baby out with the bath cytoplasm. Theres no point in trying to research it ourselves. We just need to ask the raelians how they did it. I'm sure they'll tell us if we ask really nice.
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Old 04-11-2003, 02:22 AM   #4
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Im not too convinced by this, 33 embryos is a really small sample considering the poor survival seen in most mammalian NT experiments. Im also not sure why they are so sure it is motor proteins rather than any of the number of other factors such as DNA methylation or chromatin remodelling which have previously been shown to have effects on the survival of NT embryos. Well, Ill just have to wait to read the paper.

Science has its own press release about this which goes into more detail and explains the observations they actually made on the mitotic machinery in the cells which led them to their conclusion. I think the Yahoo article was just a little too vague on the specifics.

And here is the actual paper.
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