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04-30-2003, 11:17 AM | #41 |
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Missouri Synod 2004
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04-30-2003, 11:29 AM | #42 | |
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04-30-2003, 11:45 AM | #43 | |||||||||||||||||||||||
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04-30-2003, 11:54 AM | #44 | |
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04-30-2003, 01:24 PM | #45 |
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Jim, by suggesting that proteins cannot work without an exact aa sequence you are showing a fundamental ignorance of not evolution but the very biochemistry you claim to study.
If your claim was true then the many examples of phenotypic rescue in knockouts using homologous proteins from other species, proteins with different aa sequence, would not work (your claim about proteins not studying biochemistry). Since they do work the proteins can obviously stand a few aa changes. But even your biochemistry should be sufficient to allow you to know that many of the aa's have very similar biochemical properties and consequently would not have an adverse afect in a substitution. |
04-30-2003, 02:00 PM | #46 | |
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Dear Pz,
I realise I might be rather over exaggerating with my western patriarchy comment. I am certainly not a hardcore genetic reductionist but comments such as Quote:
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04-30-2003, 03:02 PM | #47 | |
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04-30-2003, 03:22 PM | #48 | |
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04-30-2003, 03:55 PM | #49 | |
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Two points: First, that there is a heck of a lot more to evolution as a whole than mutation and selection, but you probably don't need to know too much in the way of those specifics: just keep in mind that those two factors are not the be-all and end-all. Second: You have your words in the wrong order. It should be random mutation and natural seleciton, not the other way around. This is the crucial point that you, like most evolution denyers, are missing. When you couple random mutation with the natural selection of the best mutations for survival, the end result is not random. Thats: Not Random. It has a random component, but the end result is not random at all. Here is an analogy based on poker that should help. There is a big difference in the probability of getting good hands in poker between hands simply drawn at random and hands that are then selected. If you are unfamiliar with poker, your first hand of five cards is drawn at random, and is very rarely any good. But then you get to select any number of cards you don't want, discard them and replace them. This vastly improves your chances of getting high cards in good combinations. The analogy with evolution goes like this: each generation produced by sex is like a fresh hand: some good cards, some not so great. Then, the generation of such organisms goes out in the world to make their own way. Usually, most of them die. This is equivalent to ridding your hand of the low scoring cards. The next generation fills your hand up again, but you will still be keeping you high cards, and simply filling the rest of your hand with a new set of random cards. Like poker, your second run will be much much more likely to be filled with high scoring cards, representing organisms with beneficial mutations. UNLIKE poker, you are not limited to just one redraw: it happens every single generation. Hopefully you can see that the end result is not at all random. |
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