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Old 09-17-2002, 07:09 PM   #341
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Quote:
Originally posted by Vanderzyden:
<strong>
One difficulty is that you require binary answers with no explanation. Sorry, I can't do that with the questions you are asking. The length of this thread is surely evidence of that.

Answers:

1) No. There is close similarity. But there are also immense differences when we considering entire organisms. As I have shown, homology is not the equivalent of common descent.</strong>
Well, I would reiterate to you that the DNA evidence is quite a bit stronger than you seem to think as has been demonstrated. I don't know why you would continue to argue against the idea that it at least _appears_ that common descent is true when one can easily argue, and theists do all the time, that the mechanism was God, not RM/NS.

This is a rhetorical question, but ask yourself why you were so convinced that common descent was wrong when you joined this board if, by your own admission, you had not thoroughly examined the DNA evidence.

Quote:
<strong>
2) You already know that my answer is yes. We have made only slight progress in our discussion because you will not admit that you operate daily upon the assumptions you have made regarding non-empirical phenomena:


Posted by Skeptical

"Proof" is a very strong word. At most I would say it is reasonable for each of us to believe we are in control of our own minds and reasonable for us to think that others have their own minds. It is in no way proof and it may be an especially weak hypothesis if we start postulating invisible, powerful entities that cannot be detected through any empirical means who have unknown agendas.


Ah, so you don't like the word "proof". Well, neither do I. In fact, I like the words "reasonable", "demonstration", and "persuasion". I appreciate that you say that it is reasonable to believe we are in control of our minds. That is the closest we will come to "proof". What puzzles me is that you refuse to consider other non-empirical propositions to be reasonable: </strong>
If someone could explain how we can differentiate between non-empirical causes, I'd consider them. I don't know how to go about considering them and no one has ever been able to explain how to do so that doesn't look like anything more than opinion.

Quote:
<strong>

Posted by Skeptical:

I have _experienced_ my mind, I have not _experienced_ God or Satan or aliens or any other hypothetical non-empirical entities. This is a clear difference. I have not experienced other minds, but I see what can reasonably be assumed to be the actions of other minds. As I have stated several times now, even if I grant you only 2 non-empirical entities, God and Satan, you cannot choose _even between these 2_ which of them might be the cause of particular data. That is a serious problem for anyone who wants to take the idea of non-empirical entities as causes of empirical data seriously.


Are you certain that you have not experienced God? It would seem that you insist that the experience must be direct. You must see his face, or perhaps inscriptions on the walls of Yosemite.</strong>
I have to admit I have no idea what your talking about here. I haven't been to Yosemite, I'm not even sure I've seen pictures, so I must admit ignorance.

Quote:
<strong>
To you, secondary effects are insufficient. Many people have made reasonable inferences from the created order that Something is the cause of it.</strong>
We may draw some conclusions from indirect effects, but we must have some experience that similar effects have occured from known causes. If we see a unique effect (i.e. the universe), and then posit a cause which we have no other evidence for (i.e. God), to me this is nothing more than an opinion. It is true that many people have made inferences of a creator from the "order" they see. However, we now have naturalistic explanations that are plausible for life as we see it. Even if one completely rejects the theories of evolution, this does not mean that one is inevitably required to conclude that God is the necessary reason.

Quote:
<strong>
Furthermore, it is quite easily inferred from the intricate details and exacting specifications that very special attention was given in the making of the universe (especially Earth).</strong>
If Earth was the only planet, the Sun the only star and the earth only a few thousand years old, I can see how this argument might hold weight. However, we know there are at least millions, if not hundreds of millions of stars or more, it is also reasonable to conclude that there are hundreds of millions, perhaps even billions of planets. We also know that the universe is billions of years old. These numbers are so large it is difficult for most of us to attach any real meaning to them. The fact that the number of opportunities for life to arise by chance is so large weighs heavily in favor of life arising at least _once_ by chance.

To take an analogy, if I had 100, million sided dice, the odds that on a single roll one of those dice might show up 485,657, is very small indeed. However, suppose that instead of one hundred dice, I rolled 100,000 dice. What are the odds then? Now assume that instead of rolling the dice a single time, I rolled the 100,000 dice 100,000 times? Now the chances that at least once I would get the number 485,657 are pretty good. The problem with assuming that the Earth and life on this planet "couldn't have occured by chance" are that:

1) We don't know how many dice we have (total number of planets)

2) We don't know how many sides they have
(chance of life occuring on a particular planet)

3) We don't know how many times we get to roll them (number of opportunities for organic molecules to combine in such a way that it leads to life plotted against the age of the universe)

However, we do know 1 and 3 are pretty large. 2 may be very large as well and likely is. However, given a sufficiently large 1 and 3 it seems likely that life would occur _somewhere_ on its own. To argue otherwise strikes me as just assuming a priori that we are "special", which just begs the question. "We're the only life we know of, so we must be special". To me, this is no different from assuming the Earth was the center of the universe and nothing more than human arrogance.

Quote:
<strong>
I've asked this concerning God existence in the EoG thread: Is it not possible that some people are in denial, and choose to affirm what they comfortably prefer to believe?</strong>
No offense, but this seems extraordinarily ironic coming from a theist. I wish at times I could believe that theism made sense, it would certainly make life easier, all the hard questions would be answered for me. Theism seems to be by far the most "comfortable" of the beliefs between theism, deism, agnosticism and atheism.

Quote:
<strong>
You may remember our discussion of guilt, and my hint at morality. How do you know that these do not have a supernatural cause? Note that I am not asking merely for your opinion in this case. Rather, I am asking if you are aware of a convincing demonstration.</strong>
How do I _know_ they don't? Simple, I don't. How would I know they were from a supernatural cause even if they were? The answer seems simple again, I wouldn't. How do you distinguish what someone thinks is from a "supernatural" cause from something that is just opinion?

Quote:
<strong>
I think I now understand your disposition. I will elaborate upon this at length in the BC&A thread, but let me put the short version here. Tell me if I am wrong:

You are choosing to believe what you want to believe. The requirement in any reply or evidence is that it must meet your expectations. You maintain inflexible beliefs. The questions you pose are not asked to discover the truth, but to show others that any view that is contrary to the skeptical/materialist/naturalist position is nonsense.

Is this a fair assessment?
</strong>
Not quite. A reply must make some sort of sense based on what we know about the world and the human brain. If someone wants me to consider non-empirical causes, they must specifically articulate how to do so in a way that allows me to clearly distinguish between reality and opinion. I have not seen any specifics articulated despite having asked repeatedly.

Quote:
<strong>
Here is a practical test: Name one thing that has surprised you--one thing that you thought you knew well--but turns out to be substantially different from your preconceptions. Perhaps you won't mind sharing what it is.</strong>
One thing that has suprised me is that despite having made repeated requests for you to specifically articulate how to distinguish non-empirical "knowledge" from opinion, you haven't even tried. As far as I can see, you have dealt only in generalities and every time I have offered a specific example of the problem, you have ignored it or danced around it.

BTW, if someone has researched a topic, examined the evidence and made a conclusion, do you define this as a "preconception"?

[ September 17, 2002: Message edited by: Skeptical ]</p>
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Old 09-17-2002, 08:08 PM   #342
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Quote:
Originally posted by Doubting Didymus:
<strong>

How dare you? I am simply stunned beyond belief.

This is the simgle most stupidly disrespectful act I have ever seen from you yet. There have been entire threads dealing with the quotes you presented. They were used WRONGLY, they apply to PROKARYOTES, the discrepancies are due to HORIZONTAL GENE TRANSFER and endosymbionts. They do NOT APPLY to phylogeny at multicellular levels.
</strong>
If I remember correctly, not all of the references referred to prokaryotic trees.

Anyway, my point in presenting them is to indicate that confusion abounds in phylogeny. Please understand that this is my contention.

You may also remember the <a href="http://www.mhhe.com/biosci/pae/zoology/animalphylogenetics/toc.mhtml" target="_blank">summary</a> of problems. Did you read it?

Perhaps yet another article will serve as an example of my general contention--whether one considers prokaryotic or eukaryotic phylogeny:

"Phylogenetic Classification and the Universal Tree", W. Ford Doolittle

[Science, Volume 284, Number 5423 Issue of 25 Jun 1999, pp. 2124 - 2128]

<a href="http://cas.bellarmine.edu/tietjen/Ecology/phylogenetic_classification_and_.htm" target="_blank">http://cas.bellarmine.edu/tietjen/Ecology/phylogenetic_classification_and_.htm</a>

Some interesting section titles:

-- "Methodological Problems"
-- "How Can a Phylogenetic Classification Be Preserved?"
--"LGT Challenges the Conceptual Basis of Phylogenetic Classification"
-- "What If Phylogenetic Classification Is Just Let Go?"


Quote:

(intro.)

From comparative analyses of the nucleotide sequences of genes encoding ribosomal RNAs and several proteins, molecular phylogeneticists have constructed a "universal tree of life," taking it as the basis for a "natural" hierarchical classification of all living things. Although confidence in some of the tree's early branches has recently been shaken, new approaches could still resolve many methodological uncertainties. More challenging is evidence that most archaeal and bacterial genomes (and the inferred ancestral eukaryotic nuclear genome) contain genes from multiple sources. If "chimerism" or "lateral gene transfer" cannot be dismissed as trivial in extent or limited to special categories of genes, then no hierarchical universal classification can be taken as natural. Molecular phylogeneticists will have failed to find the "true tree," not because their methods are inadequate or because they have chosen the wrong genes, but because the history of life cannot properly be represented as a tree. However, taxonomies based on molecular sequences will remain indispensable, and understanding of the evolutionary process will ultimately be enriched, not impoverished.


regarding eukaryotes:

However, modern surveys of eukaryotic gene phylogenies (22) show that many (perhaps most) enzymes involved in eukaryotic cytosolic metabolism are also of bacterial origin, not of archaeal ancestry as one would expect (Fig. 2). Resolution is, in most cases, inadequate to pinpoint bacterial sources. Most of these genes might have the same original protomitochondrial ancestry as those whose products still function in that organelle, and there is (as yet) no reason to suppose that multiple independent LGTs have played a major role in the evolution of eukaryotes since their origin. Nevertheless, serious modifications of the original endosymbiont hypothesis are called for (23), and one must ask why archaea are still considered to be the eukaryotes' closest relatives, when only a minority of eukaryotic genes may show this to be true.

conclusion:

After Zuckerkandl and Pauling (4), biologists came to think that the universal tree could be reduced to a tree based on sequences of orthologous genes, any of which (practical considerations aside) could serve as a marker for an entire genome, organism, or species. If, however, different genes give different trees, and there is no fair way to suppress this disagreement, then a species (or phylum) can "belong" to many genera (or kingdoms) at the same time: There really can be no universal phylogenetic tree of organisms based on such a reduction to genes.

To save the trees, one might define organisms as more than the sums of their genes and imagine organismal lineages to have a sort of emergent reality--just as we think of ourselves as real and continuous over a lifetime, while knowing that we contain very few of the atoms with which we were born. But, one cannot learn about the histories of such emergent entities by studying the histories of their individual parts unless arguable assumptions of the sort discussed above are made.

For prokaryotes, LGT compromises the definition of taxa at all ranks, especially the highest. Archaea (or Bacteria) may well be definable by sets of genes conserved within and not between them, but the hierarchical pattern shown in Fig. 2 is only one of many possible depictions of relationships between individual archaeal or bacterial genes and is thus not a fair (at least not complete) depiction of the actual evolutionary history of any lineage of real organisms.

Perhaps it would be easier, and in the long run more productive, to abandon the attempt to force the data that Zuckerkandl and Pauling stimulated biologists to collect into the mold provided by Darwin...
Emphasis mine.

Now, can we agree that there is no universal tree, and that phylogenetic research is inherently problematic?

Vanderzyden

[ September 17, 2002: Message edited by: Vanderzyden ]

[ September 17, 2002: Message edited by: Vanderzyden ]</p>
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Old 09-17-2002, 08:46 PM   #343
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Yes, people have made good points here about significant digits. Fine, yes, I understand that, and realized this after I posted but couldn't return directly to edit it.

My response was meant to make two points:

-- that there is a four decimal place difference in the findings that I cited. (Note that scigirl's reference made reference to "three decimal places", not significant digits.

-- the value of the gravitational constant is very small, requiring a measurement precision that is incomparable to any characteristics of hypothetical phylogenetic tree construction.

Sorry for not making that clear.

Vanderzyden
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Old 09-17-2002, 09:06 PM   #344
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All of your references refer to levels of organism where horizontal gene transfer and endosymbiosis cause problems for phylogeny AT THOSE LEVELS.

<a href="http://cas.bellarmine.edu/tietjen/Diversity/mix_and_match_in_the_tree_of_lif.htm" target="_blank">This</a> link you quoted from is about horizontal gene transfer and endosymbiosis (here referred to as 'chimerism')

A quote that I think summs up the true point of this article.

Quote:
The prevailing wisdom holds that even though eukaryotic genomes may be chimeras, prokaryotic genomes have evolved clonally and are not chimeric. Findings that challenge this viewpoint have been dismissed as exceptions, the result of investigating idiosyncratic genes or organisms (12). Now, there is growing evidence that in prokaryotes, too, horizontal gene transfer and chimerism prevail.
Nothing to do with ordinary phylogeny at multicellular levels.

<a href="http://nsmserver2.fullerton.edu/departments/chemistry/evolution_creation/web/PhilipeForterre1999.pdf" target="_blank">This</a> link deals with attempts to revise ancient phylogenies.

Again, the problems and controversies arise from lateral gene transfer and are nothing to do with phylogeny at multicellular levels.

<a href="http://www.pnas.org/cgi/content/full/95/12/6854" target="_blank">This</a> is also nothing to do with traditional multicellular phylogeny, but is an invesigation into the kind of thing the first common ancestor might have been. Again, horizontal gene transfer is an important part of this discussion.

This has all been pointed out to you within a few posts of your original, yet you are still claiming that they are relevant. What will it take? Do we need to get the scientists you are quoting to personally contact you?

Get it strait. primitive ancestral phylogeny is problematic because of gene transfer and 'chimerism' (which includes endosymbiosis). These objections do not apply to phylogeny at other levels, particularly the most relevant to us now: animal phylogeny. OK?

Your most recent quoted article is also about phylogeny problems with the rooting of the tree, referred to here as 'deep' phylogeny.

Get it? you are pointing at problems that have no bearing at all on animals.
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Old 09-17-2002, 09:20 PM   #345
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Quote:
Anyway, my point in presenting them is to indicate that confusion abounds in phylogeny
We all understand that this is what you are saying, but the 'confusion' that exists in traditional multicellular phylogeny is many orders of magnitude smaller that the discrepancy between values for G, as demonstrated by scigirls marvellous article.

The kind of thing we are looking at is nowhere near the kind of massive discrepancy your quotes imply. One of the current biggies is whether velvetworms should be in with the worms or the arthropods. Big bloody deal. As scigirls article pointed out, this is a very tiny discrepancy considering the number of possible trees that there could be disagreements about.

Yes, animal phylogenies sync up. Pick a protein gene, and you will get a remarkably similar tree. The massive discrepancies you postulate are imaginary. Find us a quote about some area of phylogeny that actually applies, and we might start to consider your idea that there is widespread disagreement.
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Old 09-17-2002, 09:45 PM   #346
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Quote:
Originally posted by Skeptical:
<strong>

To take an analogy, if I had 100, million sided dice, the odds that on a single roll one of those dice might show up 485,657, is very small indeed. However, suppose that instead of one hundred dice, I rolled 100,000 dice. What are the odds then? Now assume that instead of rolling the dice a single time, I rolled the 100,000 dice 100,000 times? Now the chances that at least once I would get the number 485,657 are pretty good. The problem with assuming that the Earth and life on this planet "couldn't have occured by chance" are that:

1) We don't know how many dice we have (total number of planets)

2) We don't know how many sides they have
(chance of life occuring on a particular planet)

3) We don't know how many times we get to roll them (number of opportunities for organic molecules to combine in such a way that it leads to life plotted against the age of the universe)

However, we do know 1 and 3 are pretty large. 2 may be very large as well and likely is. However, given a sufficiently large 1 and 3 it seems likely that life would occur _somewhere_ on its own. To argue otherwise strikes me as just assuming a priori that we are "special", which just begs the question. "We're the only life we know of, so we must be special". To me, this is no different from assuming the Earth was the center of the universe and nothing more than human arrogance.

</strong>
Think about what you have written here. To argue from a "rolling dice" analogy is to argue from a mere opinion, and rejects the "fine-tuning" that has been found in the cosmos and on our planet (size, type, of a bachelor parent star; sufficient distance from the center of the galaxy; strong and weak nuclear force; etc, etc, etc.). And, from what source do you draw the extension out to 100,000 dice? Why are the dice the planets themselves, instead of the combination of cosmological criteria? Furthermore, who is rolling the dice? Who has set up the environment in which the dice may roll? Shall I go on with such questions? This stuff is just pure invention, is it not?

This is to say nothing of your gigantic leap to "human arrogance".

Quote:
Originally posted by Skeptical:
<strong>
I wish at times I could believe that theism made sense, it would certainly make life easier, all the hard questions would be answered for me. Theism seems to be by far the most "comfortable" of the beliefs between theism, deism, agnosticism and atheism.
</strong>
Interesting. You are saying that belief in God, to which one must in someway accountable, is more comfortable to a human. I will tell you from experience and from the comments I've heard from many non-theists that the theist has the rough road, certainly in the terms of moral constraint. I do think that you touch upon the other aspect of belief: justification. It is critical to ask oneself everyday: On what basis are my beliefs warranted? Have I considered everything of importance?

Quote:
Originally posted by Skeptical:
<strong>

V:You are choosing to believe what you want to believe. The requirement in any reply or evidence is that it must meet your expectations....

S: A reply must make some sort of sense based on what we know about the world and the human brain. If someone wants me to consider non-empirical causes, they must specifically articulate how to do so in a way that allows me to clearly distinguish between reality and opinion. I have not seen any specifics articulated despite having asked repeatedly.
</strong>
You are affirming my assessment. Based upon your replies so far in this thread, I would think that we should substitute "I" for "we" above. You cannot tell me where the world comes from or how your mind is empircal, and yet you say you know how it is. You are saying, "If I can't see it, it isn't real". But, of course, I have explained at length that you live upon non-empirical assumptions every day. Of course, you deny it, and refuse to admit it directly--for fear that you will then have to concede other non-empirical causes. You have not "seen any specifics" because you refuse to consider them. Instead you hold fast to your "empirical" worldview. Remember, your position is a component of the realist view, which maintains that empircal and non-empirical phenomena are knowable. So, I agree with you by default on empirical knowledge. What you don't realize is that the burden of proof rest upon you to provide an empirical explanation for things that are obviously non-empirical.

Let me reiterate: you define "empirical" too broadly and "non-empirical" too narrowly. In fact, you effectively reject any notion of non-empirical knowledge. Am I correct?

Note: I am still waiting for you to empirically demonstrate the number 2. Starboy hinted at a good example: explain the number 2 on a slide rule.

Quote:
Originally posted by Skeptical:
<strong>

V: Here is a practical test: Name one thing that has surprised you--one thing that you thought you knew well--but turns out to be substantially different from your preconceptions. Perhaps you won't mind sharing what it is.

S: One thing that has suprised me is that despite having made repeated requests for you to specifically articulate how to distinguish non-empirical "knowledge" from opinion, you haven't even tried. As far as I can see, you have dealt only in generalities and every time I have offered a specific example of the problem, you have ignored it or danced around it.
</strong>
As seems typical with you, Skeptical, you categorically reject everything I've said. I try to see your position, but you will not try to see mine. My examples are reasonable, but you will not give one inch.

And, here again, you do not answer my inquiry. Is it not reasonable to request that you answer some of my questions now that I have attempted to answer yours?

Please tell me what else, besides any aspect of our dialogue here, has been surprising to your on your quest for knowledge? Has there been any thing of significance that has not met your expectations?

Vanderzyden
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Old 09-17-2002, 09:50 PM   #347
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Quote:
Your most recent quoted article is also about phylogeny problems with the rooting of the tree, referred to here as 'deep' phylogeny.

Get it? you are pointing at problems that have no bearing at all on animals.[/QB]
DD,

I don't see it that way. The article clearly refers to general phylogeny throughout its entire length. Did you read it?

Why didn't you respond to what I highlighted in bold?

Bottom line:

If there are problems at the root of the tree, it becomes a bush. In fact, it is nothing but a scattering of twigs on the ground.

If I put an axe at the root of the tree, it falls. Common descent from a single ancestor comes crashing to the ground.

Vanderzyden
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Old 09-17-2002, 09:54 PM   #348
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Quote:
Originally posted by Doubting Didymus:
<strong>

We all understand that this is what you are saying, but the 'confusion' that exists in traditional multicellular phylogeny is many orders of magnitude smaller that the discrepancy between values for G, as demonstrated by scigirls marvellous article.

The kind of thing we are looking at is nowhere near the kind of massive discrepancy your quotes imply. ...As scigirls article pointed out, this is a very tiny discrepancy considering the number of possible trees that there could be disagreements about.

</strong>
Marvellous? I see that you are easily impressed.

Again, I am looking for demonstrations.
You have not shown it, DD. Please do so.

Show me the precision. A simple diagram is hardly evidence.

Vanderzyden

[ September 17, 2002: Message edited by: Vanderzyden ]</p>
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Old 09-17-2002, 10:04 PM   #349
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Quote:
If there are problems at the root of the tree, it becomes a bush. In fact, it is nothing but a scattering of twigs on the ground.

If I put an axe at the root of the tree, it falls. Common descent from a single ancestor comes crashing to the ground.
The article is definitely referring to phylogeny at the domain level (bacteria, archea and eukaria). Of course I read it.

Your analogy of 'cutting the tree down' is very very stupid. Phylogeny is to do with history. Just because it encounters problems when dealing with extremely ancient history, does not mean it is unreliable for more modern history.

Your analogy is very similar to saying that if carbon dating can not return accurate results from more that 50 000 years ago, we should discard it completely.

Besides, the fact that traditional molecular phylogeny is not a reliable tool for talking about the root of the tree does not imply in the slightest that the root does not exist, or has somehow been destroyed by an axe weilding maniac, does it?
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Old 09-17-2002, 10:10 PM   #350
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Quote:
Again, I am looking for demonstrations.
You have not shown it, DD. Please do so.
I am not sure what you want to see. The accuracy of molecular phylogeny is well known, as is the remarkable way in which phylogenic trees from various molecules line up with each other.

Would a quote to this effect from a current university approved biology textbook satisfy you? I have a couple of textbooks that say precicely this.
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