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Old 10-25-2002, 02:18 PM   #161
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Quote:
Originally posted by lpetrich:<strong>
Also, the heart chambers must split in two, to split the original blood path into two blood paths. Why doesn't the heart start out with two blood paths to begin with? Doing so would avoid the risk of certain types of birth defects.
</strong>
L,

And what, precisely, is the flaw inherent in "splitting" the heart into four chambers? The human body is far more complex than fish.

There are not two blood "paths". Blood flows through one long, contiguous circuit having systemic (high pressure) and pulmonary (low pressure) sides. Actually, the design is very elegant, now that you prompt me to consider it from another aspect.

The heart is actually two pumps, a primary and and auxilliary. The primary pump is the left side, which pumps the blood "out to the body". The auxilliary pump is the right (pulmonary) side, which keeps the blood going on the last part of the circuit on its return to the lungs.

And yet, these two pumps work in tandem, and they are contained in the same organ. Simply speaking, the pulses of the heart's electrical system provide power to pumps simultaneously. Amazing!

A final note: No one has shown that the elimination of birth defects would be result from a single pump design.


John

[ October 25, 2002: Message edited by: Vanderzyden ]</p>
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Old 10-25-2002, 02:58 PM   #162
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Vanderzyden:
And what, precisely, is the flaw inherent in "splitting" the heart into four chambers? The human body is far more complex than fish.

The flaw is in the splitting, not in the heart being two sub-hearts.

Why is it necessary to start off as a single heart and have the interior split in two? Why not start off in the split-in-two configuration? Or even start off as two separate hearts?

There are not two blood "paths". Blood flows through one long, contiguous circuit having systemic (high pressure) and pulmonary (low pressure) sides. Actually, the design is very elegant, now that you prompt me to consider it from another aspect.

The two blood paths are paths through the heart, one for each sub-heart.

One interesting question is why a fish does not have similar circulation, but with blood going through the gills instead of through whatever lungs it might have.
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Old 10-25-2002, 05:24 PM   #163
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Quote:
Originally posted by lpetrich:<strong>
The flaw is in the splitting, not in the heart being two sub-hearts.

Why is it necessary to start off as a single heart and have the interior split in two? Why not start off in the split-in-two configuration? Or even start off as two separate hearts?
</strong>
Why is "splitting" a flaw? On this view, you must judge cell replication (splitting) to be a "flaw".

Two separate pumps are more inefficient, less elegant, and less compact than a tightly integrated dual pump.


John
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Old 10-25-2002, 10:28 PM   #164
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Quote:
Originally posted by Vanderzyden:
<strong>

Why is "splitting" a flaw? On this view, you must judge cell replication (splitting) to be a "flaw".

John</strong>

STRAWMAN!

Nice logic. TROLL ALERT.
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Old 10-26-2002, 02:55 AM   #165
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Gravity is utterly irrelevant when discussing fetal blood circulation.

The fetus is a fluid-filled container inside another fluid-filled container. We're discussing pumping fluids around inside a bag of other fluids. Any fluid heading up will displace an equal volume and mass of fluid heading down, and vice versa.

Underwater, a person with poor blood circulation floating in an upright position will NOT experience symptoms such as lack of blood to the brain or pooling of blood in the legs. Same principle.

...of course, this is why NASA trains astronauts in swimming pools. Assume the fetus is in a weightless environment.

[ October 26, 2002: Message edited by: Jack the Bodiless ]</p>
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Old 10-26-2002, 04:33 PM   #166
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Quote:
Originally posted by Vanderzyden:
<strong>OK, folks. Let me just drop the positive umbilical pressure/preecclampsia contention. I had a misunderstanding about something in particular that I had read. Please accept my apologies for any inconveniences caused by my failure to research that example thoroughly enough.</strong>
Apology accepted; I apologize for insulting you.

<strong>
Quote:
However, my argument concerning pressure management remains largely intact.</strong>
No, it does not. Placement of the umbilical vessels in the thorax instead of the abdomen would not significantantly impact fetal circulatory pressures. The pressures within the fetal circulation are determined by the total capacitance of its components, circulatory fluid characteristics, and the forces generated by the heart.

<strong>
Quote:
You will recall that I mentioned this at least once before. Simple laws of physics govern the pressure and velocity of fluids. So, if you take a positive, neutral or negative source and relocate it centrally in a circulatory system, the pressure map will change dramatically.</strong>
The umbilical vessels' capacitance would not be affected by relocation, and they and the placenta are not a pump; relocation as described would have no effect on circulatory pressures.

<strong>
Quote:
Observe that we are not discussing capillaries here. We are talking about a trunk line, the umbilical vein. Rick and MrD suggest placing the umbilical juncture at the present location of the terminus of the ductus arteriosus. But, again, this is inherently problematic.</strong>
There has been no proposed change in pump pressures, blood volumes, or circulatory capacitance, so there would be no effective change in fetal circulatory pressures.

<strong>
Quote:
The management of fluid pressure becomes altogether different if you move the umbilical source from

(a) an UPSTREAM location, a LONG DISTANCE from and BELOW the heart

to a location

(b) that is DOWNSTREAM, immediately ADJACENT, and ABOVE the heart.

Such a design alternative means that the heart is now "pushing" instead of "pulling" on the blood that is coming through the umbilical vein. The heart would need to be enlarged significantly, and its valves reinforced.</strong>
Absolutely not; none of the changes you assert would occur.

<strong>
Quote:
Even still, the design would be terribly poor. Why? Because the pump would not be in its proper location in this "alternative" design. Here is a simple diagram of the what MrD is suggesting:

&gt; ------- PUMP ---- INFLUENT --- EFFLUENT --------&gt; (to pump)

As you can see, there is nothing to pump. The system is grossly imbalanced. Both the influent (incoming flow from placenta) and the effluent (outgoing flow to placenta) are downstream of the pump.</strong>
This objection doesn't make sense: the placenta's blood flow in relation to the heart would not change by placing the umbilical vessels in the thorax instead of the abdomen.

<strong>
Quote:
There is another problem: another valve would need to be placed at this new junction so the blood isn't pumped back down the umbilical vein, which is at significantly LOWER PRESSURE. This would be very awkward, and certainly inelegant...</strong>
Absolutely not. It's quite clear that there would be no change in the fluid dynamics of the fetal circulation if the umbilical vessels were moved into the thorax; there would be no need for adding the superfluous valve you propose, either.

<strong>
Quote:
I have yet to see anyone here refute this argument. Until someone does, then the sub-optimal design claim remains essentially without merit.</strong>
See above.

<strong>
Quote:
Other problems with the "alternative":

-- fetal development of the right side of the heart would be significantly reduced, since the right ventricle would not need to pump (nor could it pump against the high resistence of the pulomary veins)
-- inability to have a symmetrical, aesthetically pleasing location for the umbilicus
-- the heart itself would receive the least oxygenated blood, since the coronary arteries are located on the very end of this "improved" CV system</strong>
The right heart ventricular development would not be adversely affected, humans would find a thoracic button no less aesthetic than an abdominal button if they were used to the former instead of the later, and coronary artery oxygenation would improve because the most oxygenated blood would flow to the aorta before the liver if the umbilical vessels were thoracic; anterograde coronary artery flow occurs only during diastole as a result of aortic compliance. Bringing oxygenated blood right into the thoracic vasculture after it leaves the placenta would cause more highly oxygen-saturated blood to flow into the coronary arteries than occurs with the evolved sub-optimal system that now exists.

<strong>
Quote:
Again, I will list advantages of the ductus arteriosus:

… protects lungs against circulatory overload
… allows the right ventricle to strengthen
… hi pulmonary vascular resistance, low pulmonary blood flow</strong>
The DA is an adaption necessary to compensate for the evolved inefficiencies of the fetal circulation.

Rick

[ October 26, 2002: Message edited by: rbochnermd ]</p>
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Old 10-26-2002, 05:22 PM   #167
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Quote:
Originally posted by rbochnermd:<strong>
Apology accepted; I apologize for insulting you.
</strong>
Actually, that was not the subject of my apology. I never insulted you. Not once. However, I do apologize for making a very specific error. I do appreciate your apology. Thanks.

Quote:
Originally posted by rbochnermd:<strong>
Placement of the umbilical vessels in the thorax instead of the abdomen would not significantantly impact fetal circulatory pressures. The pressures within the fetal circulation are determined by the total capacitance of its components, circulatory fluid characteristics, and the forces generated by the heart.

...
The umbilical vessels' capacitance would not be affected by relocation, and they and the placenta are not a pump; relocation as described would have no effect on circulatory pressures.
</strong>
You are correct, the placenta is not a pump. I have agreed that no additional pressure comes up the umbilical vein. However, I think you do not understand the proposal, nor my critique. See below.

Quote:
Originally posted by rbochnermd:<strong>
V: The management of fluid pressure becomes altogether different if you move the umbilical source from
(a) an UPSTREAM location, a LONG DISTANCE from and BELOW the heart

to a location

(b) that is DOWNSTREAM, immediately ADJACENT, and ABOVE the heart.

Such a design alternative means that the heart is now "pushing" instead of "pulling" on the blood that is coming through the umbilical vein. The heart would need to be enlarged significantly, and its valves reinforced.

R: Absolutely not; none of the changes you assert would occur.
</strong>
These are the changes that would necessary by MrDarwin's design "improvement". Here is his proposal (from page 2):

Quote:
Apparently I wasn’t specific enough. It’s really very simple: if the umbilical cord entered at the chest, i.e., closer to the heart, the umbilical artery could attach to the trunk of the pulmonary arteries, which would normally be taking deoxygenated blood to the lungs. With this attachment, it would take them to the placenta instead to pick up oxygen (and other nutrients). Of course a small amount of blood would still flow to the lungs, as it does in the current system....
Clearly, the suggestion is to place the umbilical vein just ABOVE the heart, attaching to the pulmonary artery.

Quote:
Originally posted by rbochnermd:<strong>
V: Even still, the design would be terribly poor. Why? Because the pump would not be in its proper location in this "alternative" design. Here is a simple diagram of the what MrD is suggesting:

&gt; ------- PUMP ---- INFLUENT --- EFFLUENT --------&gt; (to pump)

As you can see, there is nothing to pump. The system is grossly imbalanced. Both the influent (incoming flow from placenta) and the effluent (outgoing flow to placenta) are downstream of the pump.

R: This objection doesn't make sense: the placenta's blood flow in relation to the heart would not change by placing the umbilical vessels in the thorax instead of the abdomen.
</strong>
Rick, the PUMP in my diagram is the heart itself. In this design "alternative", there is nothing for the heart to pump. Let me rename the diagram:

&gt; ------- HEART ---- UMB. VEIN ---- UMB. ARTERIES --------&gt; (to heart, via the placenta)

As you can see, both the inflow (umbilical vein) and the outflow (umbilical arteries) are downsteam of the heart. The heart, which is the pump in the system, should be between the influent and the effluent. If not, then the design is not only terribly poor, but effectively inoperable.

Again, the coronary arteries receive blood that is the least oxygenated. Why? Because these arteries--which supply the heart, are located at the root of the aorta, which is BELOW the junction of the umbilical vein.

Quote:
Originally posted by rbochnermd:<strong>
The DA is an adaption necessary to compensate for the evolved inefficiencies of the fetal circulation.
</strong>
This is merely an unsubstantiated Darwinist claim. You would need to provide support in order for it to be convincing.

John

[ October 26, 2002: Message edited by: Vanderzyden ]</p>
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Old 10-26-2002, 09:19 PM   #168
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Actually, you DID insult him. Several times.
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Old 10-27-2002, 06:51 AM   #169
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Quote:
Originally posted by Vanderzyden:
<strong>the PUMP in my diagram is the heart itself. In this design "alternative", there is nothing for the heart to pump. Let me rename the diagram:

&gt; ------- HEART ---- UMB. VEIN ---- UMB. ARTERIES --------&gt; (to heart, via the placenta)

As you can see, both the inflow (umbilical vein) and the outflow (umbilical arteries) are downsteam of the heart. The heart, which is the pump in the system, should be between the influent and the effluent. If not, then the design is not only terribly poor, but effectively inoperable.

Again, the coronary arteries receive blood that is the least oxygenated. Why? Because these arteries--which supply the heart, are located at the root of the aorta, which is BELOW the junction of the umbilical vein.
</strong>
Here's how the flow would go in MrD's intelligently designed system:

vena cava&gt;right heart&gt;pulmonary trunk branching into umbilical artery and pulmonary artery &gt;placenta and lungs&gt;umbilical vein joins pulmonary veins&gt;left heart&gt;aorta and coronary arteries&gt;the brain and body&gt;vena cava.

This design obviates the need for the foramen ovale and ductus arteriosus, both of which are necessary now to compensate for the flaws in the evolved fetal circulation. The coronary arteries and the brain would both receive the most oxygenated blood in the intelligently designed system because their arterial blood would not be partially deoxygenated by any other organs as it is now. It would also do away with the potential for umbilical herniation and incarceration because the thoracic cage would be able to prevent organs from pushing through the umbilical tract as they can through the abdominal wall.

That's just one way to improve the system; you could also have the placental vein join the superior vena cava and the umbilical artery branch off of the thoracic aorta and derive the same benefits.

Rick
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Old 10-27-2002, 06:57 AM   #170
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Quote:
Originally posted by Vanderzyden:
<strong>...your posts have all the indications of the snotty, snobby, demi-god doctors that I have encountered. This is the second medical person here at Infidels with this syndrome. Why is it that so many of you are so pompous?</strong>
<strong>
Quote:
I never insulted you. Not once.</strong>
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