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Old 04-09-2003, 12:20 PM   #51
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What is that about Toxoplasma gondii protists in our brains?

I checked on the subject of toxoplasmosis, and that disease can sometimes be asymptomatic for several years, only re-emerging when one's immune system becomes weak. The Toxoplasma bugs enter a dormant state, and they wait for some opportunity to re-emerge.

So is that what Darwin's Terrier was referring to?
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Old 04-09-2003, 12:43 PM   #52
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Originally posted by Darwin's Terrier
But here’s the crux: why design it that way, and then have to design a brain mechanism to compensate for it? Unnecessarily complicated design is not good design. And a straightforward prediction from the intelligent designer hypothesis is that good designs would be used.
Your argument is still falsely assuming that maximum energetic efficiency must have been the primary goal of the intelligent designer. Value judgments about whether or not a design is "good" or "bad" is subjective, as well as peripheral to the fact that intelligent design exists at all.

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To repeat: it’s not that our eyes are poor. They’re not. But they are good despite an obvious problem. A design flaw. An imperfect design from an intelligent designer.
But by calling it a "flaw" - you are assuming that maximum energetic efficiency was the only goal of the intelligent designer. (that he/she/it subequently failed to meet) So your argument is based on an assumption that is not very sound because we have observed many motivations behind intelligent design, and maximum energetic efficiency is not the only one.

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Horsepoo. Notice much conquering of Plasmodium falciparum going on? Where are the victories over trypanosomes, schistosomes, flukes, tapeworms, hookworms, filarial nematodes, bot-flies, sand fleas, mosquitoes or lice (our own personal species)?
I think we would need to define "conquering" in order for this particular line of discussion to take on any meaning. I don't consider most of what you listed to have"conquerered" anything. They certainly affect humans, but it seems you think "affect" = "conquerer". We have treatments for all of those parasites. The very fact that we are aware of the parasites and know all about them, but they are unaware of us and know nothing, is a huge advantage for our side. Medical science is well on course for developing methods of treating/preventing parasites from being able to harm humans. So it is quite obvious who is "conquering" who in that regard. lol

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It’s already been done. There are squid.
No, it has not already been "done". A human eye designed after the squid eye has never been created and tested in a live human being. Sorry.

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The self-evident does not need much verification.
Wrong, all scientific claims require verification.

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Having the nerve wires in the way of the photons inevitably means that some are blocked or deflected, making the vision less good that it could easily have been.
You are failing to consider the possibility that rearranging the nerve wiring may cause other problems or disadvantages to arise. The bottom line is, you don't know if it would work better or not until you actually test it out in a real, flesh and blood human.


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Please quit the autoproctology and try thinking.
Please quit your autogynecology and try some manners.


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Because good design by definition means not wasting materials. The energy efficiency need not be maximum, just maximumised given other constraints. Well designed things should work as well as possible.
Now you are double-speaking. First you say energy efficiency need not be "maximum", but then say it must be "maximised as much as possible". But something that is "maximised as much as possible" means that it is operating at it's "maximum" *possible* energetic efficency. Regardless of how you want to wrangle words, your argument still breaks down to the false supposition that "maximum energetic efficiency" must be attained in all instances, and therefore, must be the primary goal of an intelligent designer, in all cases. That supposition is completely frivolous.

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I second DD’s suggestion: read the OP in the thread I linked above. And tell me why these are not stupid designs from an intelligent designer. No, really. I insist.
The arguments from "suboptimal design" falsely assume that maximum energetic efficiency must have been the primary goal of the intelligent designer in all those instances. That is a false assumption. Furthermore, value judgments about whether or not a design is "good" or "bad" is subjective and scientifically unproven, as well as peripheral to the fact that intelligent design exists at all.
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Old 04-09-2003, 01:01 PM   #53
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Originally posted by Refractor
... The arguments from "suboptimal design" falsely assume that maximum energetic efficiency must have been the primary goal of the intelligent designer in all those instances. That is a false assumption. Furthermore, value judgments about whether or not a design is "good" or "bad" is subjective and scientifically unproven, as well as peripheral to the fact that intelligent design exists at all.
But high-quality adaptation is often considered strong evidence of design. And a superpowerful designer would be able to avoid suboptimal designs. So if adaptation implies design by some superpowerful entity, then that entity ought not to have constructed suboptimal designs.
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Old 04-09-2003, 01:11 PM   #54
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The bottom line is, you don't know if it would work better or not until you actually test it out in a real, flesh and blood human.

Many mammals and birds have better vision than humans. Many have better hearing and better noses as well. Claiming that one of those "designs", or the squid eye "design", cannot be "known" to work better for humans for a particular sense without plugging it in and trying it is absurd. It's self-evident that those "designs" are better at what they do than the ones we find in us, and it is not necessary to scientifically prove that, if we had one of those designs, that particular sense would be "better".

Now, one might say that our eyes, for example, are sufficiently "designed" for our needs (at least our needs in nature, not our "civilized" needs. Better eyes might be advanateous for many modern purposes). Is that evidence of some kind of "design"? Only in the sense that there was no evolutionary selection pressure to make our eyes any better than they are.

Is the fact that the nerves in the eyes are "backwards" from an "optimal" design evidence of a designer? No; just the opposite. It's evidence of the way our eyes evolved, and that, once the "design" was set in some ancient common ancestor, it was not reversible by evolution. Thus, all descendents that inherited the original "design" are stuck with it, inefficient as it is.

What about squid eyes? Evidence of convergent evolution; eyes evolved more than once. The squid's ancestors got the nerves right from the beginning, thus all its descendence get the benefit of the more optimal design.
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Old 04-09-2003, 01:15 PM   #55
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Originally posted by Refractor
... But in short, I believe that any intelligent designer that would make something as intelligent, complex, and sentient as humans would not have done so without revealing who he/she/it is, why things were created, and what the purpose of living for is (beyond mere survival).
I think otherwise. We could just be part of a big experiment by some community of tinkerers who want to see what weird organisms we could create -- and we'd be "created" by some of these tinkerers meddling with the genes of some apes.

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Hell, even the makers of yo-yo's reveal who they are, and include directions for how their product should be used. Would the designer of human beings do anything less??
However, these messages are given to these objects' owners, and not these objects themselves. And some designers of humanity may want to hide and avoid contaminating their experiment with evidence of their presence.

Furthermore, our genes may be a good place to put a designer's signature, though there is the serious question of how one would tell that it was such a signature. Perhaps some SETI-style message?
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Old 04-09-2003, 01:16 PM   #56
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Refractor: Furthermore, value judgments about whether or not a design is "good" or "bad" is subjective and scientifically unproven, as well as peripheral to the fact that intelligent design exists at all.
Design exists in biology and in other natural phenomena, as shown in my two posts above. These design are a result of regularity and chance. The real burder on you is to demonstrate whether or not there are other designs that are intelligent. I am afraid you fall way short of this task when right off the bat you tell us:
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Your argument is still falsely assuming that maximum energetic efficiency must have been the primary goal of the intelligent designer. Value judgments about whether or not a design is "good" or "bad" is subjective, as well as peripheral to the fact that intelligent design exists at all. [...] But by calling it a "flaw" - you are assuming that maximum energetic efficiency was the only goal of the intelligent designer. (that he/she/it subequently failed to meet)
I'd say you've pretty much conceded the whole argument to us. If by your own admission noone can determine the ultimate purpose of a supposed design (i.e. a teleology), then what's the point of positing a designer? You can't even determine intent.
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Old 04-10-2003, 05:12 AM   #57
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Originally posted by lpetrich
What is that about Toxoplasma gondii protists in our brains?
It seems you’ve got a few thousand of them, probably!
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I checked on the subject of toxoplasmosis, and that disease
Ah, there you go you see: treating parasites as mere disease agents, rather than the fascinating organisms with complex ecologies and evolution in their own right!
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can sometimes be asymptomatic for several years, only re-emerging when one's immune system becomes weak. The Toxoplasma bugs enter a dormant state, and they wait for some opportunity to re-emerge.
More specifically, their ultimate hosts (I forget the exact term, it’s the host they are sexually reproductive in) are cats, not us, and they generally do not cause disease, though they can affect behaviour.
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So is that what Darwin's Terrier was referring to?
I’m referring to a bit in Carl Zimmer’s brilliant Parasite Rex:
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Plasmodium and Leishmania are fussy about where they live, able to survive only in certain types of cells. Most parasitic protozoa are equally choosy, but there are a few that can invade just about anything. One such species is Toxoplasma gondii, a creature that lives in undeserved obscurity. Few people know about Toxoplasma, even though there’s a fair chance that they are carrying it by the thousand in their brains. A third of all the people in the world are infected by it; in some parts of Europe almost everyone is a host.

[describes normal life cycle]

If a person should swallow Toxoplasma eggs, either in a speck of soil or in the meat of an infected animal, the parasite will go through this same fast-then-slow progression. Humans hardly know what’s happening during a Toxoplasma invasion; at worst it feels like a light flu. Once the parasite has retreated into its quiet cyst, a healthy person doesn’t notice it at all. It might seem as if Toxoplasma, in all its meekness, doesn’t warrant mention alongside parasites like trypanosomes and Plasmodium. But Toxoplasma actually manipulates the immune system of its host as elegantly as these other species do.

[Explains how it does so, “waiting to reach the promised land of a cat’s insides.”]

Toxoplasma becomes a threat to humans only when the cozy arrangement it creates falls apart. A fetus, for example, doesn’t have an immune system of its own. It is protected only by antibodies made by its mother that cross the placenta. The mother’s T cells are forbidden from crossing into the fetus, because they would act as if the fetus were a gigantic parasite and would kill it. Maternal antibodies do a good job against a flu virus or Escherichia coli bacteria, but they can’t protect against Toxoplasma. For that, the fetus would need inflammatory T cells to drive them into their cysts. As a result, it’s very dangerous for a woman to get a Toxoplasma infection during pregnancy. If the parasite manages to pass from her to her fetus, it will reproduce wildly. It will try to make the immune system rein it in, but inside the fetus there’s no audience to hear its calls. It simply proliferates until it causes massive, often fatal, brain damage.
(From pages 67-69.)

Ref affecting behaviour (p92-3):
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By turning rats into rodent kamikazes [disrupting the brain making the rats immune to eg the smell of cat pee], Toxoplasma probably increases its chances of getting into cats. If it makes the mistake of getting into a human instead of a rat, it has little hope of making that journey, but there’s some evidence that it still tries to manipulate its host. Psychologists have found that Toxoplasma changes the personality of its human hosts, bringing different shifts in men and women. Men become less willing to submit to the moral standards of a community, less worried about being punished for breaking society’s rules, more distrustful of other people. Women become more outgoing and warmhearted. Both changes seem to break down the fear that might keep a host out of danger. They’re hardly enough to make people throw themselves at lions, but the’re a very personal reminder of the ways in which parasites try to take control of their destiny.
Unfortunately, Zimmer’s notes don’t extend to sources for every paragraph, but there’s enough of them and they seem of high enough quality (primary literature and texts) for me to think he ain’t just making this stuff up.

Ref the kamikaze rats, see: Royal Society Proceedings B, vol 267 no. 1452, p 1591-1594: 'Fatal attraction in rats infected with Toxoplasma gondii': "Here we report that, although rats have evolved anti-predator avoidance of areas with signs of cat presence, T. gondii's manipulation appears to alter the rat's perception of cat predation risk, in some cases turning their innate aversion into an imprudent attraction."

This is a tiny iceberg-tip of parasitology -- most life, it seems, is parasitic. (I recommend A O Bush’s Parasitism too, for a readable but more formal treatment of them.) It’s why I’ve gotten so into parasites recently... after all, enough must have gotten into me...

To try to bring this thread back on track after my diversion... I wonder why the creator saw fit to design such a system?!

Cheers, DT
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Old 04-10-2003, 07:36 AM   #58
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Originally posted by Refractor
Your argument is still falsely assuming that maximum energetic efficiency must have been the primary goal of the intelligent designer.
No it’s not. It is assuming that, other things being equal, optimal designs should be found as the result of intelligent design. To repeat a bit from the thread I linked:
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It is worth bearing in mind what ‘intelligent’ really means in a design context. Manufacturing researcher and consultant Terry Hill, in his 1986/2000 book Manufacturing Strategy, notes that “any third-rate engineer can design complexity”, and goes on to say that the hallmark of truly intelligent design is not complexity, but rather simplicity, or more specifically, it is the ability to take a complex process or product spec and create the least complicated design that will meet all project parameters.
Now, can you see any reason to argue with that? It looks like common sense to me. It means, for instance, that things shouldn’t be unnecessarily convoluted, nor should excess materials be used.
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Value judgments about whether or not a design is "good" or "bad" is subjective
Of course. But the thing is, if you deny that we can tell if something is poor design, because we don’t know the designer’s intentions, then we cannot use this same system of judgement to identify good design either. If you throw out the common sense (or Hill’s logic) that says that the path of the laryngeal nerve is suboptimal, then you throw out too the common sense that says that an aerodynamic wing is a good design. We have no way to judge it.

Fine by me. It means you no longer have an argument from design.

Let me run that by you again, slowly:

Common sense says X is well-designed.

Common sense says Y is poorly designed.

If we cannot know that Y is in fact poorly designed, then we cannot know that X is well designed.

Therefore we cannot use X’s apparent good design to argue for a designer. Because, as you yourself say, such judgements are subjective, and you are rejecting our only moderately objective criteria for deciding.
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as well as peripheral to the fact that intelligent design exists at all.
Demonstrate that there is a designer, then we can talk about whether it is intelligent or not.
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No, it has not already been "done". A human eye designed after the squid eye has never been created and tested in a live human being. Sorry.
But the test is that squid eyes seem to function fine with their set-up. A set-up that does not impede incoming light. What’s to test? Do you deny that the nerves are in the way? Having something in the way of the light is bound to reduce the retina’s effectiveness.... isn’t it? :banghead:

Since that seems obvious, and since it concerns you so, please demonstrate that such an eye would not function better. Logic dictates that it should; to say it does not is counter-intuitive. So the burden of proof is in fact with you.
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DT: The self-evident does not need much verification.

Wrong, all scientific claims require verification.
Yep. And the fact that solid objects -- which neurons are -- affect the path of light has been rather well verified. Turn on a light. Look at the floor. Those dark patches are called ‘shadows’. Therefore a retina that does not have stuff in the way of the light works better than one with. :banghead:
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You are failing to consider the possibility that rearranging the nerve wiring may cause other problems or disadvantages to arise.
Nope, considered and rejected. Nothing is being re-arranged. Your designer is simply arranging, from scratch, from a blank slate. And it is poor from-scratch design to run a nerve ten or more feet out of its way, as with the giraffe’s recurrent laryngeal, because it uses more materials than necessary. (And the direct route does work fine, because (though I can’t track down the examples I’ve previously found) in rare cases the nerve does go by the logical route.)
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The bottom line is, you don't know if it would work better or not until you actually test it out in a real, flesh and blood human.
And you do not know that it wouldn’t. But in principle it should. So you do the frigging experiment.
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Please quit your autogynecology and try some manners.
Must... resist... [choice phrases deleted]

You get the respect that you deserve. Tell you what: you try thinking, and I’ll be polite.
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Now you are double-speaking. First you say energy efficiency need not be "maximum", but then say it must be "maximised as much as possible". But something that is "maximised as much as possible" means that it is operating at it's "maximum" *possible* energetic efficency.
Nope. If you drive at your car’s maximum speed, you would have your foot hard down. But other factors, like traffic, bends and visibility, mean that your optimum (which is the term that eluded me last time) speed is not the maximum one. Obviously.

But where did this “energy efficiency” bollocks come from anyway? Put it this way. Counter-current flow is a well-known method of optimising the transfer of stuff, eg heat in Leibig condensers. Not surprisingly, it is widely used in nature, in fish gills, kidneys, penguin feet and so on. But cephalopod gills are not arranged in counterflow. They are therefore less efficient than they could be. That they get round it another way is irrelevant. ‘Getting round’ something is what you do if there is an impediment in the first place.

Birds have a lung ventilation system that is through-flow, where in-coming fresh air is not mixed with used air. The mammalian tidal system, which mixes the air, is therefore less efficient. Fact. And an even more curious fact: even bats, which mirror birds in many lifestyle ways, have the tidal system. And conversely, even near-wingless kiwis have through-flow respiration.

It is a fact that parallel currents are less efficient than countercurrents.

It is a fact that tidal lung ventilation is less efficient than through-flow.

It is a fact that if something if less-efficient, it is suboptimal. By definition.

Mammal lungs and cephalopod gills are less-efficient than other methods available to the designer, and are therefore suboptimal.

And before you say it, it is not a case of bird lungs not working in mammal bodies, or of cephalopod eyes not working in human heads. The designer started with a blank slate, allegedly. And made stuff work pretty well. But, in many cases, used designs that are less efficient than he could have. To do this is not good design, since good design means using the most efficient system available. Not ‘maximum’; like your road speed, your most efficient speed is not likely to be the maximum one. Good design means being efficient.

Unless there is a good reason to do something otherwise.

Therefore the burden of proof is with you. Offer a reason why bats have a tidal ventilation system, when birds have through-flow.

To say that we cannot know the designer’s intentions for using poor designs means we cannot know that the apparently good ones really are either: it rejects the criteria for judgement. So you must do better than that.
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Regardless of how you want to wrangle words, your argument still breaks down to the false supposition that "maximum energetic efficiency" must be attained in all instances,
It would if I did say that, but I didn’t so it doesn’t. I simply say that if an apparently -- or even measurably -- poorer design is used, there has to be an explanation for this.

So offer some.
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and therefore, must be the primary goal of an intelligent designer, in all cases. That supposition is completely frivolous.
To suppose there is a from-scratch designer for things that have blatant historical constraints is completely frivolous.

TTFN, DT
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Old 04-12-2003, 02:15 PM   #59
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Originally posted by Darwin's Terrier
But here’s the crux: why design it that way, and then have to design a brain mechanism to compensate for it? Unnecessarily complicated design is not good design. And a straightforward prediction from the intelligent designer hypothesis is that good designs would be used.
The assumption appears to be that the Judaeo-Christian paradigm dictates that we are today of substantially similar physiology to Adam and Eve were upon creation. However, apocryphal writings suggest that they underwent a drastic physiological change after the fall, which was, predictably, passed on to their descendants.
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Old 04-12-2003, 04:36 PM   #60
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Originally posted by yguy
The assumption appears to be that the Judaeo-Christian paradigm dictates that we are today of substantially similar physiology to Adam and Eve were upon creation. However, apocryphal writings suggest that they underwent a drastic physiological change after the fall, which was, predictably, passed on to their descendants.
It's possible to justify anything using appropriately-invented Just So Stories.

Adam and Eve are as mythical as the first people of any other creation stories.
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