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Old 07-01-2003, 12:35 PM   #61
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Originally posted by Gurdur
Back to the spinal cord:
Anyone here want a trivia question ?
Take a guess at how long the longest neuron cell is in the human body ?
Probably proprioceptive fibers from the foot. The first synapse would be in the nucleus gracilis at the brainstem. So about 6 feet for someone pretty tall.

For a blue whale, proprioceptive fibers from the tail would be close to 120 feet, so I would guess that's the longest neuron ever.
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Old 07-01-2003, 12:43 PM   #62
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Originally posted by ps418
But I won't apologize for including detail.
Don't appologize and don't change your style. I like it. If, there is something in your posts that I don't fully comprehend, I can use the references you always provide, to educate myself. Thanks.
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Old 07-01-2003, 01:46 PM   #63
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After all, if you take a chunk of cannabis that is already cured and let it sit out for a few days, it will lose most of its potency due to oxidation.
how do you know this? please post a reference so that I can take a look, if you have one.

In my experience cannabis works better when it is left in the air. Think about the process of curing itself. People dry the cannabis so that it becomes psychoactive. I am under the impression that the oxidising process is what makes cannabis psychoactive!
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Old 07-01-2003, 04:49 PM   #64
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Originally posted by ps418
The second observation, even more interesting, is that, strange as it may seem, cannabinoids have actually been demonstrated to have tumor-supressor properties in vitro, on a variety of cancer types!
Weed: Is there anything it can't do?

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Old 07-02-2003, 05:44 AM   #65
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Originally posted by theyeti
Weed: Is there anything it can't do?
The stems do not work very well for cleaning your pipe.
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Old 07-02-2003, 05:47 AM   #66
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Originally posted by sweep
how do you know this? please post a reference so that I can take a look, if you have one.
This is an observation I made many times in my smoking days. Times may vary from sample to sample, depending on density and so on, but with dry, not-so-dense commercial grade cannabis, even a few days sitting out, particularly in sunlight, can make a big difference. Though not addressing this issue directly, you can find some information on cannabis degradation

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In my experience cannabis works better when it is left in the air. Think about the process of curing itself. People dry the cannabis so that it becomes psychoactive.
As I made clear, I was referring to plants that are already cured. And, AFIK, curing just allows the moisture in the plant to evaporate, making it combustible, and preventing the growth of mold on the plant once its stored, rather than actually increasing the psychoactive content.

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I am under the impression that the oxidising process is what makes cannabis psychoactive!
Well, one of the things oxidation does is convert your THC to the nonpsychoactive CBN, cannabinol. As long as your stash is subject to oxygen, this is happening. Think of it as a very slow burn. This is a major reason why cannabis loses its potency over time.

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Old 07-02-2003, 05:55 AM   #67
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Originally posted by theyeti
Weed: Is there anything it can't do?

theyeti
Yes. It absolutely can not help you with your diet (unless you're diet consists of brownies, in which case it helps quite a bit).

Patrick
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Old 07-02-2003, 08:35 AM   #68
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Default how much did you get into cannabis use?

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This is an observation I made many times in my smoking days. Times may vary from sample to sample, depending on density and so on, but with dry, not-so-dense commercial grade cannabis, even a few days sitting out, particularly in sunlight, can make a big difference.
we'll have to agree to disagree here. According to yourself, it loses most of its potency after a few days. I've owned some very dry flowerheads before, kept them in a bag the whole summer, and the high was always as fresh. (aside from the part where I became immune to smoking it neat and had to have a weeks break)

A guy I 'knew' had MS and used cannabis to keep his nerves working good. He sold me some 'top of the plant' material. It was well cured, but still slightly soft. after a couple of weeks it was solid with sap, almost as though it were glazed. If I squeezed a bit between my fingers It would shatter. Very dusty, and very potent. Now, Thai Grass, which is commercially available in Amsterdam resembles what we call 'bush' over here- so called because it is brown and possibly very old. Since THC degrades and turns into cannabidiol over time, this is going to mean that the smoke is a 'heavier hit'. Thai grass, from most Bulldog coffeeshops in the Dam, is quite heavy.

Now, I'm having trouble working out what you mean by 'commercially available' since commercially available in Amsterdam means- it's there to buy in many flavours and strengths. It is never, apart from bottom of the plant joint filler, 'low-density cannabis'. This stuff, I recall tends to be very light, low in sap, and not very frosty. To be blunt, its shit to start with, and if it were commercially available here, I wouldn't get it.

Quote:
As I made clear, I was referring to plants that are already cured. And, AFIK, curing just allows the moisture in the plant to evaporate, making it combustible, and preventing the growth of mold on the plant once its stored, rather than actually increasing the psychoactive content.
As far as I feel, when I tried uncured cannabis, it didn't work. This has to be because the cannabis is non-psychoactive when wet.

Perhaps with very dense, sticky flowers, when cured (the way it should be) air can't get to the inside of the bud, leaving the THC intact?

EDITED TO ADD:
Quote:
even a few days sitting out, particularly in sunlight, can make a big difference
this point bothers me. I don't know whether it was a feeling based observation or one based upon scientific knowledge, but I dare not suggest that ps418 is using 'hazy' memories and juvenile logic to conclude that sunlight destroys thc. You see, in the flowering stage of a cannabis plants development, a cultivator will use high pressure sodium bulbs to simulate the autumn sun. Something in the properties of this light (I don't know why) causes the cannabis plant to produce psychoactive elements. So why it would be that real sunlight, possibly with a different spectrum of light, destroys THC evades me???
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Old 07-02-2003, 10:26 AM   #69
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Default Re: how much did you get into cannabis use?

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Originally posted by sweep
we'll have to agree to disagree here. According to yourself, it loses most of its potency after a few days. I've owned some very dry flowerheads before, kept them in a bag the whole summer
Disagree all you want, but you're not disagreeing with what I actually wrote. I said letting a small piece of cannabis "sit out for a few days," NOT keeping them in a bag. As far as the loss being "most" or "some," as I said this depends on things like the density of the cannabis. To be more precise, let me change most to "a significant amount."


Quote:
sweep:
Now, I'm having trouble working out what you mean by 'commercially available' since commercially available in Amsterdam means
Fair point. By commercial I mean the vast majority of pot in the US, which is fairly low-grade sativa, mostly grown in Mexico, certainly not like what you find in Amsterdam.


Quote:
sweep: this point bothers me. I don't know whether it was a feeling based observation or one based upon scientific knowledge, but I dare not suggest that ps418 is using 'hazy' memories and juvenile logic to conclude that sunlight destroys thc.
No, its a simple fact based on my own observation. Its also supported by the references I gave, as well as by cannabis botany manuals. That you think this at all controversial is odd.

Quote:
Solutions of pure cannabinoids, nine samples of herbal and two of resin cannabis (one freshly prepared) were stored in varying conditions for up to 2 years. Exposure to light (not direct sunlight) was shown to be the greatest single factos in loss of cannabinoids especially in solutions, which should therefore be protected from light during analytical and phytochemical operations.
The stability of cannabis and its preparations on storage
Fairbairn JW, Liebmann JA, Rowan MG
J Pharm Pharmacol 1976 Jan;28(1):1-7

And by chapter 4 of Marijuana Botany, by by Robert Connell Clarke, which states that:

Quote:
THC decomposes to CBN in the hot sun and will not remain intact or be replaced after the metabolic processes of the plant have ceased. Since cannabinoids are so sensitive to decomposition by sunlight, the higher psychoactivity of amber resins may be a secondary effect.
. . .
Glass jars and plastic freezer bags are the most common containers for the storage of floral clusters. Polyethylene plastic sandwich or trash bags are not suited to long-term storage since they breathe air and water vapor. This may cause the floral clusters to dry out excessively and lose potency. Heat-sealed boilable plastic pouches do not breathe and are frequently used for storage. Glass canning jars are also very air-tight, but glass breaks. It is feared by some connoisseurs that plastic may also impart an unpleasant taste to the floral clusters. In either case, additional care is usually taken to protect the floral clus ters from light so another opaque container is used to cover the clear glass or plastic wrapping. Clusters are not sealed permanently until they have finished curing. Curing involves the presence of oxygen, and sealing floral clusters will end the free exchange of oxygen and end curing. However, oxygen also causes the slow breakdown of THC to CBN, so after the curing process is completed, the container is completely sealed. Any oxygen present in the container will be used up and no more can enter. Nitrogen has been suggested as a packing medium because it is very non-reactive and inexpensive. Jars or bags may be flooded with nitrogen to displace air and then sealed. Vacuum-sealing machines are available for Mason jars and may be modified to vacuum-sealed bags.

Quote:
sweep:
You see, in the flowering stage of a cannabis plants development, a cultivator will use high pressure sodium bulbs to simulate the autumn sun. Something in the properties of this light (I don't know why) causes the cannabis plant to produce psychoactive elements. So why it would be that real sunlight, possibly with a different spectrum of light, destroys THC evades me???
Gosh, I was unaware that plants need sunlight to grow! One difference you are overlooking is that before you harvest the plant, the plant is alive and actively synthesizing cannabinoids, while after harvest, the plant is dead, and active synthesis of new cannabinoids ceases. Does this distinction evade you too?

Patrick
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Old 07-02-2003, 11:10 AM   #70
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Lightbulb I didn't seem sarcastic did I? sorry

Quote:
Disagree all you want, but you're not disagreeing with what I actually wrote. I said letting a small piece of cannabis "sit out for a few days," NOT keeping them in a bag. As far as the loss being "most" or "some," as I said this depends on things like the density of the cannabis. To be more precise, let me change most to "a significant amount."
I acknowledged that you took flower density into account. I questioned the conditions. If the small piece of cannabis was in the sun then the sunlight, according to the interesting study you referred me to, was a primary factor in the fast decline in THC and not the air. Hence the confusion (I should have said I kept it a brown paper bag)

Quote:
Fair point. By commercial I mean the vast majority of pot in the US, which is fairly low-grade sativa, mostly grown in Mexico, certainly not like what you find in Amsterdam.
but surely you can't extrpolate your own experiences of buying pot in your own environment to the entire United States? unless..? I'll dare bet there is plenty of good pot in north america. Did you ever get any decent stuff? If so, please give me a description.

Quote:
No, its a simple fact based on my own observation. Its also supported by the references I gave, as well as by cannabis botany manuals. That you think this at all controversial is odd.
given my ignorance between the recently elucidated 'dead' cannabis and synthesis 'on the plant', the controversy should be understandable. however, I am simply interested in learning, so I will tolerate what you overlooked.

Quote:
Gosh, I was unaware that plants need sunlight to grow! One difference you are overlooking is that before you harvest the plant, the plant is alive and actively synthesizing cannabinoids, while after harvest, the plant is dead, and active synthesis of new cannabinoids ceases. Does this distinction evade you too?
my point was that sodium bulbs are used to aid the growth of flowers on the cannabis plant. Without these the cannabis isn't as strong. I assumed that the light was key in synthesising thc. I know how to grow good cannabis, but I don't know why thc is synthesised, or how to maximise thc synthesis. I shall have to find out. I apologise for not thinking deeply enough.

thanks for the botany link too.

I WROTE:

Quote:
Think about the process of curing itself. People dry the cannabis so that it becomes psychoactive. I am under the impression that the oxidising process is what makes cannabis psychoactive!
and from the botany link:

Quote:
Curing takes this process one step farther to produce tasty and psychoactive marijuana. If drying occurs too rapidly, the green taste will be sealed into the tissues and may remain there indefinitely. A floral cluster is not dead after harvest any more than an apple is. Certain metabolic activities take place for some time, much like the ripening and eventual spoiling of an apple after it is picked. During this period, cannabinoid acids decarboxylate into the psychoactive cannabinoids and terpenes isomerize to create new polyterpenes with tastes and aromas different from fresh floral clusters. It is suspected that cannabinoid biosynthesis may also continue for a short time after harvest.
so... 2 points. sythesis DOES take place after the flower has been picked, but not the synthesis of new thc??, although this is suspected. And curing, accordingto the study, makes the flowers psychoactive. Unless this guy is wrong, of course.
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