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Old 05-20-2003, 07:47 AM   #11
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Originally posted by Advocatus Diaboli
Hmmm. I was under the impression that immunity to HIV came from a deletion. Live and learn.
It does. A deletion can clearly be a beneficial mutation, just as a substitution or addition can be.

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Old 05-20-2003, 07:57 AM   #12
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Originally posted by Dr. Evil
If you want to stay out of the arena of diseases you could do a search about genetic traits in athelets. I've heard about a study in which they took muscle biopsies of athletes and examined them for different characteristics that seperate them from mere mortals like ourselves (I was told that one of the subjects was Lance Armstrong and that his muscle profile had some interesting characteristics). I haven't seen this with my own eyes so take it with a grain of salt.
There is at least one allele signficantly associated with increased aerobic endurance -- the "I/D" polymorphism of the angiotensin converting enzyme, though the association is not very strong.

Montgomery et al, Human gene for physical performance. Nature 393, 221 - 222, 1998.

Woods et al, The ACE I/D polymorphism and human physical performance. Trends Endocrinol Metab 2000 Dec;11(10):416-20.

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